Practicalities of Shared-Decision Making for Stroke Prevention: Relevance to PFO Closure and LAA Occlusion
Operator and Institutional Requirements for PFO Closure for Secondary Prevention of Paradoxical Embolic Stroke
The prematurely stopped and underpowered trial failed to meet its primary endpoint but was consistent with prior positive trials.
But an outside source questioned the decision to lump CREST together with EVA-3S, SPACE, and ICSS.
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In addition, an infarct in a new territory did not emerge as an independent predictor of functional outcome.
The procedure—a hybrid of surgical and endovascular techniques—offers low stroke rates and a short learning curve.
Hyperintense acute reperfusion marker on MRI portends worse outcomes and may help identify patients needing adjunctive care.
The randomized trial is on schedule, while the registry is training a generation of operators, CREST-2 investigators said at ISET 2018.
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