Practicalities of Shared-Decision Making for Stroke Prevention: Relevance to PFO Closure and LAA Occlusion
Operator and Institutional Requirements for PFO Closure for Secondary Prevention of Paradoxical Embolic Stroke
Clopidogrel added to rivaroxaban and aspirin increased bleeding with no added protection from limb or CV events.
Although rivaroxaban patients had more bleeding, the events were not severe and none were intracranial or fatal.
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The strokes do not appear related to valve thrombosis or structural degeneration, but rather to high risk in general.
In addition, an infarct in a new territory did not emerge as an independent predictor of functional outcome.
The procedure—a hybrid of surgical and endovascular techniques—offers low stroke rates and a short learning curve.
Hyperintense acute reperfusion marker on MRI portends worse outcomes and may help identify patients needing adjunctive care.
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