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Sapien 3 Stroke Rate Perplexes in 1-Year SOLVE-TAVI Results
Stroke rates for the balloon-expandable device far exceeded those of the Evolut R; conscious sedation was also a clear winner.
Efficacy Eludes TriGUARD 3 Cerebral Protection Device: REFLECT II
Safety goals were met in the trial, but better efficacy may require ensuring complete coverage of the three major cerebral vessels.
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The strokes do not appear related to valve thrombosis or structural degeneration, but rather to high risk in general.
In addition, an infarct in a new territory did not emerge as an independent predictor of functional outcome.
The procedure—a hybrid of surgical and endovascular techniques—offers low stroke rates and a short learning curve.
Hyperintense acute reperfusion marker on MRI portends worse outcomes and may help identify patients needing adjunctive care.
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